Annotation Detail

Information
Associated Genes
CXCL10
Associated Variants
rs12980275
IFNL4 c.151-152G>A ( ENST00000606380.2 )
NC_000019.10:g.39252525T>G
rs12980275
IFNL4 c.151-152G>A ( ENST00000606380.2 )
NC_000019.10:g.39252525T>G
Associated Disease
Hepatitis C, Chronic
Source Database
DisGeNET
Description
To assess the role of the ss469415590 variant, compared with the known IL28B polymorphisms (rs8099917, rs12979860 and rs12980275) for predicting virological response to therapy in chronic hepatitis C, and its association with the CXCL10 chemokine serum levels - a surrogate marker of interferon-stimulated genes activation.
Pubmed
24308755
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00843456107781768
Year of publication
2013
Drugs