Annotation Detail
Information
- Associated Genes
- IFNL3
- Associated Variants
-
IFNL4 c.151-152G>A
(
ENST00000606380.2 )
IFNL4 c.151-152G>A ( ENST00000606380.2 ) - Associated Disease
- Hepatitis C, Chronic
- Source Database
- DisGeNET
- Description
- IL-28B rs12979860 C/T polymorphism T allele is more prevalent in patients with viral cirrhosis due to HCV in comparison to other aetiologies and to patients with mild chronic hepatitis C. Among OLT patients, carriage of this allele seems to augment the risk of developing HCC.
- Pubmed
- 21146242
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0948429671860937
- Year of publication
- 2011
Drugs