Annotation Detail
Information
- Associated Genes
- MC4R
- Associated Variants
-
rs12970134
rs4450508
MLXIPL p.Gln241His (p.Q241H) ( ENST00000313375.8, ENST00000354613.5, ENST00000414749.6, ENST00000429400.6, ENST00000434326.5 )
rs12970134
rs4450508
MLXIPL p.Gln241His (p.Q241H) ( ENST00000313375.8, ENST00000354613.5, ENST00000414749.6, ENST00000429400.6, ENST00000434326.5 ) - Associated Disease
- Diabetes Mellitus, Non-Insulin-Dependent
- Source Database
- DisGeNET
- Description
- Here, we evaluated the association of two variants (rs12970134 and rs4450508) near MC4R and a nonsynonymous (Gln241His) variant (rs3812316) in MLXIPL gene with type 2 diabetes (T2D) and obesity-related QTs in our case-control cohort (n = 1,528; 745 T2D cases and 783 controls) from a Sikh population from North India.
- Pubmed
- 19680233
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0293705990997067
- Year of publication
- 2010
Drugs