Annotation Detail
Information
- Associated Genes
- INSIG2
- Associated Variants
-
FTO c.46-27405G>C
(
ENST00000636218.1,
ENST00000636491.1,
ENST00000637001.1,
ENST00000637969.1,
ENST00000471389.6 )
FTO c.46-23525T>A ( ENST00000636491.1, ENST00000636218.1, ENST00000471389.6, ENST00000637969.1, ENST00000637001.1 )
FTO c.46-13587A>G ( ENST00000637969.1, ENST00000637001.1, ENST00000471389.6, ENST00000636491.1, ENST00000636218.1 )
rs17782313
rs12970134
rs7566605
INSIG2 c.-139+768T>C ( ENST00000245787.9 )
INSIG2 c.370-439C>T ( ENST00000245787.9 )
FTO c.46-27405G>C ( ENST00000471389.6, ENST00000636218.1, ENST00000636491.1, ENST00000637001.1, ENST00000637969.1 )
FTO c.46-23525T>A ( ENST00000471389.6, ENST00000636218.1, ENST00000636491.1, ENST00000637001.1, ENST00000637969.1 )
FTO c.46-13587A>G ( ENST00000471389.6, ENST00000636218.1, ENST00000636491.1, ENST00000637001.1, ENST00000637969.1 )
rs17782313
rs12970134
rs7566605
INSIG2 c.-139+768T>C ( ENST00000245787.9 )
INSIG2 c.370-439C>T ( ENST00000245787.9 ) - Associated Disease
- Non-alcoholic Fatty Liver Disease
- Source Database
- DisGeNET
- Description
- Our aim was to identify whether the obesity-susceptible gene variants (rs9939609, rs9930506, and rs4783819 in fat mass and obesity-associated gene (FTO); rs12970134 and rs17782313 in melanocortin-4 receptor gene (MC4R); and rs7566605, rs13428113, and rs9308762 in insulin-induced gene 2 [INSIG2]) were associated with NAFLD.
- Pubmed
- 24458218
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2015
Drugs