Annotation Detail

Information
Associated Genes
PPARG
Associated Variants
PPARG MUTATION
PPARG MUTATION
Associated Disease
ischemia
Source Database
DisGeNET
Description
Nitroalkene derivatives of oleic acid (OA-NO2) serve as high-affinity ligand for PPAR-γ, which regulates apoptosis, oxidation and inflammation and plays a central role in ischemia-reperfusion injury.
Pubmed
25766531
Section of the abstract supporting the evidence
BACKGROUND
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree,CTD_human,LHGDN
DisGENET score for the Gene Disease association
0.123267233986628
Drugs