Annotation Detail

Information
Associated Genes
CHRNA3
Associated Variants
CHRNA3 c.378-4117G>A ( ENST00000326828.6, ENST00000348639.7 )
CHRNA3 c.378-4117G>A ( ENST00000326828.6, ENST00000348639.7 )
Associated Disease
Chronic Obstructive Airway Disease
Source Database
DisGeNET
Description
Analysis of 6633 individuals with moderate to severe COPD and 5704 control individuals confirmed association at three known loci: CHRNA3 (p=6·38 × 10(-14)), FAM13A (p=1·12 × 10(-14)), and HHIP (p=1·57 × 10(-12)).
Pubmed
24621683
Original source reporting the Gene Disease association
GWASCAT
DisGENET score for the Gene Disease association
0.129077133910489
Year of publication
2014
Drugs