Annotation Detail

Information
Associated Genes
IL2RA
Associated Variants
IL2RA c.64+5006A>G ( ENST00000256876.10, ENST00000447847.2, ENST00000697424.1, ENST00000379959.8, ENST00000379954.5 )
IL2RA c.64+2039G>A ( ENST00000256876.10, ENST00000447847.2, ENST00000379959.8, ENST00000379954.5, ENST00000697424.1 )
IL2RA c.64+5006A>G ( ENST00000256876.10, ENST00000379954.5, ENST00000379959.8, ENST00000447847.2, ENST00000697424.1 )
IL2RA c.64+2039G>A ( ENST00000256876.10, ENST00000379954.5, ENST00000379959.8, ENST00000447847.2, ENST00000697424.1 )
Associated Disease
multiple sclerosis
Source Database
DisGeNET
Description
Genome-wide association studies have identified an association between two intronic single nucleotide polymorphisms (SNPs), rs12722489 and rs2104286, in the interleukin-2 receptor alpha-chain gene (IL2RA) and susceptibility to multiple sclerosis (MS).
Pubmed
21239413
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.303190007587811
Year of publication
2011
Drugs