Annotation Detail
Information
- Associated Genes
- CASP8
- Associated Variants
-
CASP8 p.Asp344His (p.D344H)
(
ENST00000264275.9,
ENST00000323492.11,
ENST00000358485.8,
ENST00000392263.6,
ENST00000413726.6,
ENST00000432109.6,
ENST00000440732.6,
ENST00000444430.3,
ENST00000450491.6,
ENST00000673742.1,
ENST00000696067.1,
ENST00000696069.1,
ENST00000696085.1,
ENST00000696087.1 )
rs889312
CASP8 p.Asp344His (p.D344H) ( ENST00000264275.9, ENST00000323492.11, ENST00000358485.8, ENST00000392263.6, ENST00000413726.6, ENST00000432109.6, ENST00000440732.6, ENST00000444430.3, ENST00000450491.6, ENST00000673742.1, ENST00000696067.1, ENST00000696069.1, ENST00000696085.1, ENST00000696087.1 )
rs889312 - Associated Disease
- Malignant neoplasm of pancreas
- Source Database
- DisGeNET
- Description
- CASP8 rs1045485 [odds ratio (OR), 0.78; 95% confidence interval (95% CI), 0.65-0.9; P = 0.005] and MAP3K1 rs889312 (OR, 0.85; 95% CI, 0.74-0.97; P = 0.017) showed evidence of association with risk of pancreatic cancer.
- Pubmed
- 19843670
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00135720936040152
- Year of publication
- 2009
Drugs