Annotation Detail
Information
- Associated Genes
- IL1RL1
- Associated Variants
-
SH2B3 p.Trp262Arg (p.W262R)
(
ENST00000341259.7,
ENST00000538307.1 )
IL1RL1 c.610+428C>T ( ENST00000233954.6, ENST00000311734.6, ENST00000404917.6, ENST00000409584.5 )
rs12619285
rs4431128
WDR36 c.410-798C>T ( ENST00000513710.4 )
ENSG00000283782 c.-168-31999T>G
rs9494145
TNXB c.-9+459C>T ( ENST00000375244.7, ENST00000479795.1, ENST00000644971.2, ENST00000647633.1 )
rs748065
rs3939286
SH2B3 p.Trp262Arg (p.W262R) ( ENST00000341259.7, ENST00000538307.1 )
IL1RL1 c.610+428C>T ( ENST00000233954.6, ENST00000311734.6, ENST00000404917.6, ENST00000409584.5 )
rs12619285
rs4431128
WDR36 c.410-797C>T ( ENST00000513710.4 )
ENSG00000283782 c.-168-31999T>G
rs9494145
TNXB c.-9+459C>T ( ENST00000375244.7, ENST00000479795.1, ENST00000644971.2, ENST00000647633.1 )
rs748065
rs3939286 - Associated Disease
- Eosinophilia
- Source Database
- DisGeNET
- Description
- We recruited 284 patients with NP in four participating hospitals in Belgium and 427 healthy controls, and genotyped 10 SNPs affecting eosinophilia (rs1420101 in IL1RL1, rs12619285 in IKZF2, rs4431128 in GATA2, rs4143832 in IL5, rs3184504 in SH2B3, rs2416257 in WDR36, rs2269426 in MHC, rs9494145 in MYB, rs748065 in GFRA2, and rs3939286 in IL33) using MALDI-TOF.
- Pubmed
- 19860791
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00081432561624091
- Year of publication
- 2010
Drugs