Annotation Detail

Information
Associated Genes
GCKR
Associated Variants
GCKR p.Leu446Pro (p.L446P) ( ENST00000264717.7 )
GCKR p.Leu446Pro (p.L446P) ( ENST00000264717.7 )
Associated Disease
Metabolic syndrome X
Source Database
DisGeNET
Description
A polymorphism in the GCKR gene predicted dyslipidaemia (rs1260326, OR 1.15, 95% CI 1.09-1.22, p < 0.00001) but not the metabolic syndrome.
Pubmed
18853134
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.128729747168288
Year of publication
2008
Drugs