Annotation Detail
Information
- Associated Genes
- GCKR
- Associated Variants
-
GCKR p.Leu446Pro (p.L446P)
(
ENST00000264717.7 )
GCKR p.Leu446Pro (p.L446P) ( ENST00000264717.7 ) - Associated Disease
- hyperglycemia
- Source Database
- DisGeNET
- Description
- Moreover, an additive effect of GCKR rs1260326(T) and GCK (-30G) alleles conferred lower fasting glycemia (P = 1 x 10(-13)), insulinemia (P = 5 x 10(-6)), and hyperglycemia risk (P = 1 x 10(-6)).
- Pubmed
- 18556336
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00135720936040152
- Year of publication
- 2008
Drugs