Annotation Detail

Information
Associated Genes
GCKR
Associated Variants
G6PC2 c.441-26T>C ( ENST00000375363.8, ENST00000421979.1, ENST00000429379.2 )
GCKR p.Leu446Pro (p.L446P) ( ENST00000264717.7 )
G6PC2 c.441-26T>C ( ENST00000375363.8, ENST00000421979.1, ENST00000429379.2 )
GCKR p.Leu446Pro (p.L446P) ( ENST00000264717.7 )
Associated Disease
Diabetes Mellitus, Insulin-Dependent
Source Database
DisGeNET
Description
The study group included 129 children with GCK-MODY from the Polish Registry of Monogenic Diabetes and 395 with type 1 diabetes (T1DM), in whom we genotyped 2 SNPs in G6PC2 (rs560887) and GCKR (rs1260326).
Pubmed
24918535
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Year of publication
2015
Drugs