Annotation Detail

Information
Associated Genes
GCKR
Associated Variants
GCKR p.Leu446Pro (p.L446P) ( ENST00000264717.7 )
GCKR p.Leu446Pro (p.L446P) ( ENST00000264717.7 )
Associated Disease
Diabetes Mellitus, Non-Insulin-Dependent
Source Database
DisGeNET
Description
The common P446L polymorphism in GCKR inversely modulates fasting glucose and triglyceride levels and reduces type 2 diabetes risk in the DESIR prospective general French population.
Pubmed
18556336
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.162020084608958
Year of publication
2008
Drugs