Annotation Detail

Information
Associated Genes
ESR2
Associated Variants
ESR2 c.*39G>A ( ENST00000556275.5, ENST00000553796.5, ENST00000555278.5, ENST00000353772.7, ENST00000341099.6, ENST00000554572.5, ENST00000557772.5, ENST00000267525.10, ENST00000358599.9 )
ESR2 p.Val328= (p.V328=) ( ENST00000556275.5, ENST00000553796.5, ENST00000353772.7, ENST00000341099.6, ENST00000554572.5, ENST00000555278.5, ENST00000557772.5, ENST00000358599.9, ENST00000267525.10 )
ESR2 c.-91+2334T>G ( ENST00000554572.5, ENST00000358599.9 )
ESR2 c.*39G>A ( ENST00000267525.10, ENST00000341099.6, ENST00000353772.7, ENST00000358599.9, ENST00000553796.5, ENST00000554572.5, ENST00000555278.5, ENST00000556275.5, ENST00000557772.5 )
ESR2 p.Val328= (p.V328=) ( ENST00000267525.10, ENST00000341099.6, ENST00000353772.7, ENST00000358599.9, ENST00000553796.5, ENST00000554572.5, ENST00000555278.5, ENST00000556275.5, ENST00000557772.5 )
ESR2 c.-91+2334T>G ( ENST00000358599.9, ENST00000554572.5 )
Associated Disease
obesity
Source Database
DisGeNET
Description
The relationship of three polymorphisms (rs1271572, rs1256049 and rs4986938) and their associated haplotypes in the ESR2 gene with obesity and overweight were evaluated in 561 apparently healthy women (median age 63 years) from the Women's Health Study.
Pubmed
19111408
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0874484826780071
Year of publication
2009
Drugs