Annotation Detail

Information
Associated Genes
GCK
Associated Variants
GCK MUTATION
GCK MUTATION
Associated Disease
hypoglycemia
Source Database
DisGeNET
Description
Biochemical and structural analysis of this loop variant and GCK variants associated with hyperinsulinemic hypoglycemia reveal two distinct mechanisms of enzyme activation.
Pubmed
26283387
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
5
Original source reporting the Gene Disease association
BeFree,GAD,LHGDN
DisGENET score for the Gene Disease association
0.00997733591851466
Drugs