Annotation Detail

Information
Associated Genes
MEN1
Associated Variants
MEN1 MUTATION
MEN1 MUTATION
Associated Disease
hypoglycemia
Source Database
DisGeNET
Description
Suppression of β-catenin signalling by genetic ablation or a molecular antagonist inhibits the expression of proproliferative genes in menin-null PNETs and potently improves hyperinsulinemia and hypoglycemia in mice.
Pubmed
25517963
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
6
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.00263847385068233
Drugs