Annotation Detail

Information
Associated Genes
SREBF2
Associated Variants
SREBF2 p.Gly595Ala (p.G595A) ( ENST00000361204.9, ENST00000710853.1 )
SCAP p.Val798Ile (p.V798I) ( ENST00000265565.10, ENST00000648151.1 )
SREBF2 p.Gly595Ala (p.G595A) ( ENST00000361204.9, ENST00000710853.1 )
SCAP p.Val798Ile (p.V798I) ( ENST00000265565.10, ENST00000648151.1 )
Associated Disease
myocardial infarction
Source Database
DisGeNET
Description
SREBF-2 1784G > C single nucleotide polymorphism (SNP, rs2228314) and SCAP 2386A > G variant (rs12487736) are associated with early onset myocardial infarction (MI) and sudden cardiac death in middle-aged men.
Pubmed
20111910
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00326723398662778
Year of publication
2011
Drugs