Annotation Detail
Information
- Associated Genes
- SRD5A1
- Associated Variants
-
SRD5A2 c.281-4722G>A
(
ENST00000622030.2 )
SRD5A2 c.280+16701C>T ( ENST00000622030.2 )
SRD5A2 p.Ala88= (p.A88=) ( ENST00000622030.2 )
rs676033
NSUN2 c.359+2056C>T ( ENST00000264670.11, ENST00000506139.5 )
SRD5A1 c.294-8108G>A ( ENST00000274192.7 )
SRD5A2 c.282-4722G>A ( ENST00000622030.2 )
SRD5A2 c.281+16701C>T ( ENST00000622030.2 )
SRD5A2 p.Leu89Val (p.L89V) ( ENST00000622030.2 )
rs676033
NSUN2 c.359+2056C>T ( ENST00000264670.11, ENST00000506139.5 )
SRD5A1 c.294-8108G>A ( ENST00000274192.7 ) - Associated Disease
- Metastatic Prostate Carcinoma
- Source Database
- DisGeNET
- Description
- We studied the polymorphisms rs518673 and rs166050 in SRD5A1, and rs12470143, rs523349, rs676033 and rs2208532 in SRD5A2 as well as the time to CRPC progression and overall survival in 104 patients with metastatic prostate cancer that had undergone primary ADT.
- Pubmed
- 26169017
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
- Year of publication
- 2015
Drugs