Annotation Detail
Information
- Associated Genes
- CHRNB3
- Associated Variants
-
CHRNA5 p.Asp398Asn (p.D398N)
(
ENST00000299565.9,
ENST00000559554.5 )
CHRNA3 c.*546C>T ( ENST00000348639.7, ENST00000326828.6 )
CHRND c.1048-1116T>G ( ENST00000258385.8, ENST00000543200.5 )
rs13277254
CHRNA5 p.Asp398Asn (p.D398N) ( ENST00000299565.9, ENST00000559554.5 )
CHRNA3 c.*546C>T ( ENST00000326828.6, ENST00000348639.7 )
CHRND c.1048-1116T>G ( ENST00000258385.8, ENST00000543200.5 )
rs13277254 - Associated Disease
- nicotine dependence
- Source Database
- DisGeNET
- Description
- Here we test the hypothesis that the nicotinic receptor genes CHRNA5 (rs16969968), CHRNA3 (rs578776), CHRNB3 (rs13277254) and CHRND (rs12466358) modify the risk for nicotine dependence associated with peer smoking.
- Pubmed
- 20840187
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00616721818772628
- Year of publication
- 2010
Drugs