Annotation Detail
Information
- Associated Genes
- LTA4H
- Associated Variants
-
ALOX5 c.431+100A>G
(
ENST00000374391.7,
ENST00000542434.5 )
LTA4H c.1380-684A>G ( ENST00000552789.5, ENST00000228740.7, ENST00000413268.6 )
ALOX5AP c.241+2366A>T ( ENST00000617770.4, ENST00000380490.5 )
ALOX5 c.431+100A>G ( ENST00000374391.7, ENST00000542434.5 )
LTA4H c.1380-684A>G ( ENST00000228740.7, ENST00000413268.6, ENST00000552789.5 )
ALOX5AP c.241+2366A>T ( ENST00000380490.5, ENST00000617770.4 ) - Associated Disease
- Ischemic Cerebrovascular Accident
- Source Database
- DisGeNET
- Description
- In combined analysis of multiple genes and loci, individuals with ALOX5AP rs12429692 T allele, ALOX5 rs2029253 A allele, and LTA4H rs6538697 C allele suggested a significantly increased susceptibility to IS (adjusted OR, 1.70; 95% CI, 1.07-2.69; P=0.024).
- Pubmed
- 23079278
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
- Year of publication
- 2012
Drugs