Annotation Detail
Information
- Associated Genes
- IRS2
- Associated Variants
-
IRS2 MUTATION
IRS2 MUTATION - Associated Disease
- Hypertensive disease
- Source Database
- DisGeNET
- Description
- Thus, preserved stimulation of proximal tubule transport through the insulin/IRS2/PI3-K pathway may play an important role in the pathogenesis of hypertension associated with metabolic syndrome.
- Pubmed
- 25354240
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 8
- Original source reporting the Gene Disease association
- BeFree,GAD
- DisGENET score for the Gene Disease association
- 0.00263847385068233
Drugs