Annotation Detail
Information
- Associated Genes
- ADH1B
- Associated Variants
-
ADH1B p.His48Arg (p.H48R)
(
ENST00000305046.13,
ENST00000506651.5,
ENST00000625860.2 )
ADH1B p.His48Arg (p.H48R) ( ENST00000305046.13, ENST00000506651.5, ENST00000625860.2 ) - Associated Disease
- Alcohol abuse
- Source Database
- DisGeNET
- Description
- Given the logistic and ethical constraints that would be associated with a trial of alcohol use to prevent depression, we aimed to complete a Mendelian randomization study to determine if a genetic polymorphism associated with alcohol abuse and dependence (ADH1B rs1229984 G-->A) contributed to modulate the risk of depression in a community-derived cohort of older men.
- Pubmed
- 24018899
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0255704128905824
- Year of publication
- 2013
Drugs