Annotation Detail
Information
- Associated Genes
- ADH1C
- Associated Variants
-
NAA25 c.403-2510C>T
(
ENST00000261745.9 )
CHRNA5 p.Asp398Asn (p.D398N) ( ENST00000299565.9, ENST00000559554.5 )
CHRNA3 c.*546C>T ( ENST00000348639.7, ENST00000326828.6 )
ADH1B p.His48Arg (p.H48R) ( ENST00000305046.13, ENST00000506651.5, ENST00000625860.2 )
ADH1C p.Ile350Phe (p.I350F) ( ENST00000515683.6 )
ADH1C p.Ile350Val (p.I350V) ( ENST00000515683.6 )
ADH7 p.Gly100Ala (p.G100A) ( ENST00000209665.8, ENST00000437033.7, ENST00000476959.5, ENST00000482593.5 )
NAA25 c.403-2510C>T ( ENST00000261745.9 )
CHRNA5 p.Asp398Asn (p.D398N) ( ENST00000299565.9, ENST00000559554.5 )
CHRNA3 c.*546C>T ( ENST00000326828.6, ENST00000348639.7 )
ADH1B p.His48Arg (p.H48R) ( ENST00000305046.13, ENST00000506651.5, ENST00000625860.2 )
ADH1C p.Ile350Phe (p.I350F) ( ENST00000515683.6 )
ADH1C p.Ile350Val (p.I350V) ( ENST00000515683.6 )
ADH7 p.Gly100Ala (p.G100A) ( ENST00000209665.8, ENST00000437033.7, ENST00000476959.5, ENST00000482593.5 ) - Associated Disease
- nicotine dependence
- Source Database
- DisGeNET
- Description
- We investigated six variants known to influence nicotine addiction or alcohol metabolism, including rs16969968 (CHRNA5), rs578776 (CHRNA3), rs1229984 (ADH1B), rs698 (ADH1C), rs1573496 (ADH7), and rs4767364 (ALDH2).
- Pubmed
- 24505444
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2014
Drugs