Annotation Detail
Information
- Associated Genes
- CYP2A13
- Associated Variants
-
CYP2A13 p.Arg101Ter (p.R101*)
(
ENST00000330436.4 )
ADH1B p.His48Arg (p.H48R) ( ENST00000305046.13, ENST00000506651.5, ENST00000625860.2 )
ADH1C p.Ile350Phe (p.I350F) ( ENST00000515683.6 )
ADH1C p.Ile350Val (p.I350V) ( ENST00000515683.6 )
ADH1C p.Arg48Leu (p.R48L) ( ENST00000515683.6 )
ADH1C p.Arg48His (p.R48H) ( ENST00000515683.6 )
CYP2A13 p.Arg101Ter (p.R101*) ( ENST00000330436.4 )
ADH1B p.His48Arg (p.H48R) ( ENST00000305046.13, ENST00000506651.5, ENST00000625860.2 )
ADH1C p.Ile350Phe (p.I350F) ( ENST00000515683.6 )
ADH1C p.Ile350Val (p.I350V) ( ENST00000515683.6 )
ADH1C p.Arg48Leu (p.R48L) ( ENST00000515683.6 )
ADH1C p.Arg48His (p.R48H) ( ENST00000515683.6 ) - Associated Disease
- pancreatic carcinoma
- Source Database
- DisGeNET
- Description
- Based on the assumption that genetic variation in carcinogen metabolism further modifies the risk of exposure-related cancers, we studied the association of polymorphisms in the tobacco carcinogen-metabolizing gene CYP2A13 (Arg101Stop) and the alcohol-metabolizing genes ADH1B (Arg48His) and ADH1C (Ile350Val) with pancreatic cancer risk.
- Pubmed
- 19812523
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
- Year of publication
- 2010
Drugs