Annotation Detail

Information
Associated Genes
ADH1B
Associated Variants
ADH1B p.His48Arg (p.H48R) ( ENST00000305046.13, ENST00000506651.5, ENST00000625860.2 )
ADH1B p.His48Arg (p.H48R) ( ENST00000305046.13, ENST00000506651.5, ENST00000625860.2 )
Associated Disease
Malignant neoplasm of esophagus
Source Database
DisGeNET
Description
Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk.
Pubmed
19698717
Original source reporting the Gene Disease association
GWASCAT
DisGENET score for the Gene Disease association
0.158100346267995
Year of publication
2009
Drugs