Annotation Detail

Information
Associated Genes
IRS2
Associated Variants
IRS2 MUTATION
IRS2 MUTATION
Associated Disease
hyperinsulinism
Source Database
DisGeNET
Description
These studies have shown that IRS2 is critically required for beta-cell compensation in conditions of increased insulin demand.
Pubmed
24977713
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
5
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00081432561624091
Drugs