Annotation Detail
Information
- Associated Genes
- AKR1B1
- Associated Variants
-
AKR1B1 MUTATION
AKR1B1 MUTATION - Associated Disease
- hyperglycemia
- Source Database
- DisGeNET
- Description
- We present a novel mechanism for miR-24 downregulation through hyperglycemia-induced activation of aldose reductase, reactive oxygen species, and c-Myc.
- Pubmed
- 25814526
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree,RGD
- DisGENET score for the Gene Disease association
- 0.0832573024649636
Drugs