Annotation Detail

Information
Associated Genes
NOS3
Associated Variants
NOS3 MUTATION
NOS3 MUTATION
Associated Disease
hyperglycemia
Source Database
DisGeNET
Description
HHcy and HG induced ED, which was potentiated by the combination of HHcy and HG via μ-calpain/PKCβ2 activation-induced eNOS-pThr497/495 and eNOS inactivation.
Pubmed
25352635
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
15
Original source reporting the Gene Disease association
BeFree,CTD_human,GAD,LHGDN
DisGENET score for the Gene Disease association
0.126991475325631
Drugs