Annotation Detail
Information
- Associated Genes
- BRCA1
- Associated Variants
-
TCF7L2 c.552+9017G>T
(
ENST00000538897.5,
ENST00000352065.10,
ENST00000369397.8,
ENST00000355995.9,
ENST00000534894.5,
ENST00000369395.6,
ENST00000277945.12,
ENST00000355717.9,
ENST00000545257.6,
ENST00000629706.2,
ENST00000627217.3,
ENST00000704414.1 )
TCF7L2 c.552+9017G>T ( ENST00000277945.12, ENST00000352065.10, ENST00000355717.9, ENST00000355995.9, ENST00000369395.6, ENST00000369397.8, ENST00000534894.5, ENST00000538897.5, ENST00000545257.6, ENST00000627217.3, ENST00000629706.2, ENST00000704414.1 ) - Associated Disease
- Breast Cancer, Familial
- Source Database
- DisGeNET
- Description
- We investigated the effect of the TCF7L2 rs12255372 variant on familial breast cancer (BC) risk by means of TaqMan allelic discrimination, analyzing BRCA1/2 mutation-negative index patients of 592 German BC families and 735 control individuals.
- Pubmed
- 17109766
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.195656337440284
- Year of publication
- 2006
Drugs