Annotation Detail
Information
- Associated Genes
- PPARGC1A
- Associated Variants
-
PPARGC1A p.Gly482Ser (p.G482S)
(
ENST00000264867.7,
ENST00000613098.4 )
ENPP1 p.Lys173Gln (p.K173Q) ( ENST00000647893.1 )
ADRB3 p.Trp64Arg (p.W64R) ( ENST00000345060.5 )
PPARGC1A p.Gly482Ser (p.G482S) ( ENST00000264867.7, ENST00000613098.4 )
ENPP1 p.Lys173Gln (p.K173Q) ( ENST00000647893.1 )
ADRB3 p.Trp64Arg (p.W64R) ( ENST00000345060.5 ) - Associated Disease
- Diabetes Mellitus, Non-Insulin-Dependent
- Source Database
- DisGeNET
- Description
- Under an additive genetic model, the C allele of ADRB3-rs4994, the C allele of ENPP1-rs1044498, and the A allele of PPARGC1A-rs8192678 increase the risk of type 2 diabetes in the Chinese Han population.
- Pubmed
- 22391941
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.287121837724248
- Year of publication
- 2012
Drugs