Annotation Detail

Information
Associated Genes
PDLIM5
Associated Variants
FHL1 p.Trp122Ser (p.W122S) ( ENST00000370676.7, ENST00000370683.6, ENST00000394153.6, ENST00000394155.8, ENST00000535737.5, ENST00000539015.5, ENST00000543669.5, ENST00000618438.4, ENST00000628568.1, ENST00000628919.3, ENST00000629039.2, ENST00000630084.2, ENST00000651089.1, ENST00000651929.2, ENST00000652457.1 )
FHL1 p.Trp122Ser (p.W122S) ( ENST00000370676.7, ENST00000370683.6, ENST00000394153.6, ENST00000394155.8, ENST00000535737.5, ENST00000539015.5, ENST00000543669.5, ENST00000618438.4, ENST00000628568.1, ENST00000628919.3, ENST00000629039.2, ENST00000630084.2, ENST00000651089.1, ENST00000651929.2, ENST00000652457.1 )
Associated Disease
myopathy
Source Database
DisGeNET
Description
In 2008, we identified a missense mutation in the second LIM domain of FHL1 (c.365 G>C, p.W122S) in a family with SP myopathy.
Pubmed
25274776
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00081432561624091
Year of publication
2015
Drugs