Annotation Detail

Information
Associated Genes
IRF4
Associated Variants
RALY c.877-563A>G ( ENST00000246194.8, ENST00000375114.7 )
IRF4 c.492+386C>T ( ENST00000380956.9, ENST00000696871.1 )
RALY c.877-563A>G ( ENST00000246194.8, ENST00000375114.7 )
IRF4 c.492+386C>T ( ENST00000380956.9, ENST00000696871.1 )
Associated Disease
Spot pigmented
Source Database
DisGeNET
Description
We identified genome-wide significant association with pigmented spots at three genetic loci: IRF4 (rs12203592, P=1.8 × 10(-27)), MC1R (compound heterozygosity score, P=2.3 × 10(-24)), and RALY/ASIP (rs6059655, P=1.9 × 10(-9)).
Pubmed
25705849
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Year of publication
2015
Drugs