Annotation Detail

Information
Associated Genes
HCL1
Associated Variants
IRF4 c.492+386C>T ( ENST00000380956.9, ENST00000696871.1 )
IRF4 c.492+386C>T ( ENST00000380956.9, ENST00000696871.1 )
Associated Disease
Lymphoma, Large-Cell, Follicular
Source Database
DisGeNET
Description
Analysis of joint effects between eye and hair color with the IRF4 rs12203592 SNP did not reveal statistically significant p-interactions although NHL risk did decline with lighter hair color and presence of the variant IRF4 rs12203592 allele, compared to those without a variant allele and with black/brown hair color.
Pubmed
19396635
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Year of publication
2009
Drugs