Annotation Detail

Information
Associated Genes
IDUA
Associated Variants
SLC26A1 c.*917C>T, IDUA p.Arg89Gln (p.R89Q) ( ENST00000247933.9, ENST00000514224.2, ENST00000361661.6, ENST00000398516.3, ENST00000398520.6, ENST00000622731.4 )
SLC26A1 c.*917C>T, IDUA p.Arg89Gln (p.R89Q) ( ENST00000247933.9, ENST00000514224.2, ENST00000361661.6, ENST00000398516.3, ENST00000398520.6, ENST00000622731.4 )
Associated Disease
mucopolysaccharidosis I
Source Database
DisGeNET
Description
The alpha-L-iduronidase mutations R89Q and R89W result in an attenuated mucopolysaccharidosis type I clinical presentation.
Pubmed
14559116
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.152798316216588
Year of publication
2003
Drugs