Annotation Detail

Information
Associated Genes
TPM3
Associated Variants
TPM3 p.Arg168His (p.R168H) ( ENST00000330188.13, ENST00000368530.7, ENST00000302206.9, ENST00000328159.9, ENST00000368533.8, ENST00000323144.12, ENST00000271850.11, ENST00000368531.6, ENST00000611659.5, ENST00000651641.1 )
TPM3 p.Arg168His (p.R168H) ( ENST00000271850.11, ENST00000302206.9, ENST00000323144.12, ENST00000328159.9, ENST00000330188.13, ENST00000368530.7, ENST00000368531.6, ENST00000368533.8, ENST00000611659.5, ENST00000651641.1 )
Associated Disease
Myopathies, Nemaline
Source Database
DisGeNET
Description
We also report a sixth family in which a recurrent TPM3 mutation (p.Arg168His) was associated with histological features of CFTD and nemaline myopathy in different family members.
Pubmed
18300303
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0156974782755293
Year of publication
2008
Drugs