Annotation Detail

Information
Associated Genes
TGM1
Associated Variants
TGM1 p.Asp490Gly (p.D490G) ( ENST00000544573.5, ENST00000206765.11 )
TGM1 p.Gly278Arg (p.G278R) ( ENST00000206765.11, ENST00000544573.5 )
TGM1 p.Asp490Gly (p.D490G) ( ENST00000206765.11, ENST00000544573.5 )
TGM1 p.Gly278Arg (p.G278R) ( ENST00000206765.11, ENST00000544573.5 )
Associated Disease
Self-Healing Collodion Baby
Source Database
DisGeNET
Description
In two self-healing collodion baby siblings with markedly diminished epidermal transglutaminase 1 activity we found the compound heterozygous transglutaminase 1 mutations G278R and D490G.
Pubmed
12542526
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Year of publication
2003
Drugs