Annotation Detail

Information
Associated Genes
NR5A1
Associated Variants
NR5A1 p.Gly35Glu (p.G35E) ( ENST00000373588.9, ENST00000620110.4 )
NR5A1 p.Gly35Glu (p.G35E) ( ENST00000373588.9, ENST00000620110.4 )
Associated Disease
Adrenal gland hypofunction
Source Database
DisGeNET
Description
Not long ago, a mutation (G35E) in the human SF-1 gene was identified as the cause of sex reversal and adrenal failure in a phenotypically female but genotypically XY individual.
Pubmed
12907682
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.128067311292288
Year of publication
2003
Drugs