Annotation Detail
Information
- Associated Genes
- CASP9
- Associated Variants
-
CASP9 MUTATION
CASP9 MUTATION - Associated Disease
- HIV Infections
- Source Database
- DisGeNET
- Description
- These data suggest that HIV-1 causes a mitochondrial initiated apoptotic cascade, which signal through caspase-9, whereas HIV-1 infected MDM causes apoptosis predominantly via the death-receptor pathway, mediated by caspase-8.
- Pubmed
- 25329893
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 11
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
Drugs