Annotation Detail

Information
Associated Genes
FGFR2
Associated Variants
FGFR2 c.1087+1304G>A ( ENST00000357555.9, ENST00000683211.1, ENST00000369061.8, ENST00000346997.6, ENST00000682772.1, ENST00000457416.7, ENST00000684153.1, ENST00000356226.8, ENST00000478859.5, ENST00000613048.4, ENST00000682550.1, ENST00000638709.2, ENST00000369056.5, ENST00000360144.7, ENST00000358487.10, ENST00000369060.8, ENST00000351936.11, ENST00000369059.5 )
FGFR2 c.1087+1304G>A ( ENST00000346997.6, ENST00000351936.11, ENST00000356226.8, ENST00000357555.9, ENST00000358487.10, ENST00000360144.7, ENST00000369056.5, ENST00000369059.5, ENST00000369060.8, ENST00000369061.8, ENST00000457416.7, ENST00000478859.5, ENST00000613048.4, ENST00000638709.2, ENST00000682550.1, ENST00000682772.1, ENST00000683211.1, ENST00000684153.1 )
Associated Disease
Craniofacial dysostosis type 1
Source Database
DisGeNET
Description
Skulls of Fgfr2(C342Y/+) mice differ from normal littermates in a comparable manner with differences between the skulls of humans with Crouzon syndrome and those of unaffected individuals.
Pubmed
17105336
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.332486326115694
Year of publication
2006
Drugs