Annotation Detail

Information
Associated Genes
PPOX
Associated Variants
PPOX p.Arg59Trp (p.R59W) ( ENST00000352210.9, ENST00000535223.5, ENST00000367999.9, ENST00000544598.5, ENST00000462866.5 )
PPOX p.Arg59Trp (p.R59W) ( ENST00000352210.9, ENST00000367999.9, ENST00000462866.5, ENST00000535223.5, ENST00000544598.5 )
Associated Disease
variegate porphyria
Source Database
DisGeNET
Description
A R59W mutation in human protoporphyrinogen oxidase results in decreased enzyme activity and is prevalent in South Africans with variegate porphyria.
Pubmed
8673113
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.457577708336763
Year of publication
1996
Drugs