Annotation Detail
Information
- Associated Genes
- CYP19A1
- Associated Variants
-
CYP19A1 c.*19C>T
(
ENST00000396404.8,
ENST00000396402.6,
ENST00000559878.5 )
ESR1 p.Ser10= (p.S10=) ( ENST00000206249.8, ENST00000338799.9, ENST00000406599.5, ENST00000440973.5, ENST00000443427.5, ENST00000456483.3 )
ESR1 p.Ser10= (p.S10=) ( ENST00000206249.8, ENST00000338799.9, ENST00000406599.5, ENST00000440973.5, ENST00000443427.5, ENST00000456483.3 )
CYP19A1 c.*19C>T ( ENST00000396402.6, ENST00000396404.8, ENST00000559878.5 )
ESR1 p.Ser10= (p.S10=) ( ENST00000206249.8, ENST00000338799.9, ENST00000406599.5, ENST00000440973.5, ENST00000443427.5, ENST00000456483.3 )
ESR1 p.Ser10= (p.S10=) ( ENST00000206249.8, ENST00000338799.9, ENST00000406599.5, ENST00000440973.5, ENST00000443427.5, ENST00000456483.3 ) - Associated Disease
- Malignant neoplasm of prostate
- Source Database
- DisGeNET
- Description
- The combination of the TTTA long repeats and the minor alleles of rs10046 in CYP19A1 and rs2077647 in ESR-alpha was a high risk for prostate cancer despite greater than or equal to 60 mg isoflavones/day.
- Pubmed
- 19952760
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.0508693839090846
- Year of publication
- 2010
Drugs