Annotation Detail

Information
Associated Genes
TTR
Associated Variants
TTR p.Gly73Glu (p.G73E) ( ENST00000237014.8, ENST00000610404.5, ENST00000649620.1 )
TTR p.Gly73Glu (p.G73E) ( ENST00000237014.8, ENST00000610404.5, ENST00000649620.1 )
Associated Disease
Plaque, Amyloid
Source Database
DisGeNET
Description
A sural nerve biopsy disclosed amyloid deposits, which led to the identification of a rare heterozygous transthyretin mutation (p.Glu74Gly; old classification: p.Glu54Gly).
Pubmed
25471118
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0179151635573
Year of publication
2014
Drugs