Annotation Detail

Information
Associated Genes
POLG
Associated Variants
POLG p.Gly737Arg (p.G737R) ( ENST00000442287.6, ENST00000268124.11, ENST00000636937.2 )
POLG p.Gly737Arg (p.G737R) ( ENST00000268124.11, ENST00000636937.2, ENST00000442287.6 )
POLG p.Gly737Arg (p.G737R) ( ENST00000268124.11, ENST00000442287.6, ENST00000636937.2 )
POLG p.Gly737Arg (p.G737R) ( ENST00000268124.11, ENST00000442287.6, ENST00000636937.2 )
Associated Disease
PROGRESSIVE EXTERNAL OPHTHALMOPLEGIA WITH MITOCHONDRIAL DNA DELETIONS, AUTOSOMAL RECESSIVE
Source Database
DisGeNET
Description
Early-onset familial parkinsonism due to POLG mutations.
Pubmed
16634032
Original source reporting the Gene Disease association
UNIPROT
DisGENET score for the Gene Disease association
0.480542883744161
Year of publication
2006
Drugs