Annotation Detail
Information
- Associated Genes
- TET2
- Associated Variants
-
TET2 MUTATION
TET2 MUTATION - Associated Disease
- Hematological Disease
- Source Database
- DisGeNET
- Description
- The methylcytosine dioxygenase TET2 is frequently mutated in hematological disorders, including acute myeloid leukemia (AML), and has been suggested to protect CG dinucleotide (CpG) islands and promoters from aberrant DNA methylation.
- Pubmed
- 25886910
- Section of the abstract supporting the evidence
- ALL_TEXT_1/3
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 2
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00190009310456212
Drugs