Annotation Detail

Information
Associated Genes
MYH7
Associated Variants
MYH7 p.Arg403Leu (p.R403L) ( ENST00000713768.1, ENST00000355349.4, ENST00000713769.1 )
MYH7 p.Arg403Gln (p.R403Q) ( ENST00000355349.4, ENST00000713768.1, ENST00000713769.1 )
MYH7 p.Arg403Leu (p.R403L) ( ENST00000355349.4, ENST00000713768.1, ENST00000713769.1 )
MYH7 p.Arg403Gln (p.R403Q) ( ENST00000355349.4, ENST00000713768.1, ENST00000713769.1 )
Associated Disease
hypertrophic cardiomyopathy
Source Database
DisGeNET
Description
Faster cross-bridge detachment and increased tension cost in human hypertrophic cardiomyopathy with the R403Q MYH7 mutation.
Pubmed
24928957
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0544602604195234
Year of publication
2015
Drugs