Annotation Detail

Information
Associated Genes
MPL
Associated Variants
MPL MUTATION
MPL MUTATION
MPL p.Trp515Leu (p.W515L) ( ENST00000372470.9, ENST00000413998.7 )
JAK2 p.Val617Ile (p.V617I) ( ENST00000381652.4 )
JAK2 p.Val617Phe (p.V617F) ( ENST00000381652.4 )
MPL p.Trp515Leu (p.W515L) ( ENST00000372470.9, ENST00000413998.7 )
JAK2 p.Val617Ile (p.V617I) ( ENST00000381652.4 )
JAK2 p.Val617Phe (p.V617F) ( ENST00000381652.4 )
Associated Disease
Thrombocythemia, Essential
Source Database
DisGeNET
Description
JAK2 V617F and MPL W515L/K mutations in Korean patients with essential thrombocythemia.
Pubmed
20890078
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.288954139976145
Year of publication
2010
Drugs