Annotation Detail

Information
Associated Genes
MPL
Associated Variants
MPL p.Trp515Leu (p.W515L) ( ENST00000372470.9, ENST00000413998.7 )
MPL p.Trp515Leu (p.W515L) ( ENST00000372470.9, ENST00000413998.7 )
Associated Disease
Thrombocythemia 2
Source Database
DisGeNET
Description
MPLW515L is a novel somatic activating mutation in myelofibrosis with myeloid metaplasia.
Pubmed
16834459
Original source reporting the Gene Disease association
UNIPROT
DisGENET score for the Gene Disease association
0.12
Year of publication
2006
Drugs