Annotation Detail

Information
Associated Genes
MPL
Associated Variants
MPL p.Trp515Leu (p.W515L) ( ENST00000372470.9, ENST00000413998.7 )
MPL p.Trp515Leu (p.W515L) ( ENST00000372470.9, ENST00000413998.7 )
Associated Disease
leukemia
Source Database
DisGeNET
Description
We conclude that MPL(W515L) occurs in a considerable proportion of acute megakaryoblastic leukaemias with myelofibrosis unrelated to PMF.
Pubmed
19194467
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0051673270911899
Year of publication
2009
Drugs