Annotation Detail

Information
Associated Genes
MPL
Associated Variants
MPL p.Trp515Leu (p.W515L) ( ENST00000372470.9, ENST00000413998.7 )
MPL p.Trp515Leu (p.W515L) ( ENST00000372470.9, ENST00000413998.7 )
Associated Disease
myelofibrosis
Source Database
DisGeNET
Description
Evidence for MPL W515L/K mutations in hematopoietic stem cells in primitive myelofibrosis.
Pubmed
17709604
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.363528744337044
Year of publication
2007
Drugs