Annotation Detail

Information
Associated Genes
MPL
Associated Variants
MPL p.Trp515Leu (p.W515L) ( ENST00000372470.9, ENST00000413998.7 )
MPL p.Trp515Leu (p.W515L) ( ENST00000372470.9, ENST00000413998.7 )
Associated Disease
Myeloproliferative disease
Source Database
DisGeNET
Description
To investigate its prevalence in Chinese patients with MPD, we introduced allele-specific PCR (AS-PCR) combined with sequence analysis to simultaneously screen MPL W515L and JAK2 V617F mutations in 190 MPD patients.
Pubmed
18464114
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0366335162974183
Year of publication
2008
Drugs